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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '589dc5785bd6325393fdd36c72a940b29b6e0d13cdb33ec6ea648e0401eb807f' 
  AND token = 'u7UmjdlI1p/gDupEunc4LljyHZNfUP3288w5iq/mBKk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}