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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6a04c91189c1fc077400e8e6d00721b68ad8ac0592d13051983a5636fc431a2' 
  AND token = 'kK0w6gYcmF8dFjs3S5l+vM/EhliJpFUiXM1t/8Or5sA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}