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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7378173d3cededdf8a5aa5346e633856f685e7e41c44238584ad2544b8049e25' 
  AND token = 'yG8vmOadpTn82pcPga9GpXFqmk7Ivo+gbYEgq5xv/Zo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}