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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09ed3d6c8139a7910d07a058bcd7fdd002e5103d2142b5f8b6bbcdd6e0f738c7' 
  AND token = 'XfcJSnDItBkBHI0Mkqa3nt3hN4UFOtryfRs/KSD7btk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}