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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '356b08f39ccc8d5ffe64084da9db79b9c56aad584928336dc0d5fb01a32dabc0' 
  AND token = 'huARVt7S3f3C60cVzUyvbAqvWsHZRLPPBFCoZmOw6WI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}