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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0530db511de213fac319499bc521aac8d1644f70ed34981dd719366c3b5d2343' 
  AND token = 'XUN8BwEb4e3IVlyfVYFgtpA3+QwduNSMcAPIPrM2kwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}