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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc4446afc5f7081734fb0615aa58e1e05d13c0779b1294fc43b074b605f40e63' 
  AND token = '+X08sk+e1Oer63jlZoH+FOUvWHu3Djocxm+ddo82M2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}