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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b345400c8568a8b57292169213f44a46182ef3531a6f4156d255af1f71a5fee3' 
  AND token = 'kGF4JbxICpCjXLLdbFWscV1PQVuW4uW1tfmU7a8vSE4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}