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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3fe13d51dd62e7fcc210857bbdbe5a81b6c80300e2bf814de361b3208e65b27' 
  AND token = 'vz66L+SYDoSZatMhyLx4AoQZ4HK6QUVSQ4DDkZpKEbI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}