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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1325df0db9c6e59a190a2eb648da158e85fda9dc0fdf963d3dc0925eddb3bebc' 
  AND token = '/ot+O33zPp27l1NzEtvXnlJgPx3oBsXgDx6mZn7wYTY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}