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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5acc5019dae82301224570755fc1b55c3ec61c8e6833e7d1ffaa9d32a3d4310c' 
  AND token = 'dPuNnBXYuS6nQT1T3lYmGAiJA3tnZ/gkgAZD69hV6/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}