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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9722d0f8cadc7ae59ce45774ba28c5519ac3496d9f48bb1b85be944f4ebd4d14' 
  AND token = 'IiXJcbpYkeRQ7zFvYmrtSP1HqC9yz4bA+RakRzX1nXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}