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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e59d548599fcd2d4f759e0e961eea21eb136c0228480fd7e7cacc1905a56c3f' 
  AND token = 'yweiuOEZEqKeKkbOH4cu+18hJrRVKEynRHOYp+K6SKU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}