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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '157e5822830f4ceb6eb3f8057d4915472c07787e0e4c9c6d0eb2a6098b0b6560' 
  AND token = 'qw2++1nWhrzLp3sij8cWG5jc6GKcDJSdR3DBltKrztc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}