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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03cbf67402a7273d1bee7d444f0f0a95313a50659c8b118a05aa596aa59ad644' 
  AND token = 'F0iGop6GSwAIrH3TuDJPsxOzO9hs2UjW92R2WNci4bw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}