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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b043d65df64f7a28e9f967e4f683a1ad4e562885c72a0e2450e31e49f1ed4fc5' 
  AND token = 'QZCkMqec23J1f1+ia60fGMUq7jftzpqp7PqO8g2ULqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}