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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06ce13daab11f242e87e2d0f64aaf44f4680e04d6a43824a3f18145827eb3be8' 
  AND token = 'U2Uu4BgBXDvnZTLG0h2+sJl36V20GfiulwcGhLQJYPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}