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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '445f503eddf9e3fd8947bb39736a6c92b70d8c5e3ae3e6857012f699025b13d0' 
  AND token = 'fmce3K+PjZItoZPZaJi89ZlUQdKA3iGjW4GfEu2HJeg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}