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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e887c5043db28d697c9c761530f645adfdfb5a6d261b9c04efe900bb8cf1a937' 
  AND token = 'qX67aujuAiwM1KNpJ+5EIDiuo3HCa5sz5H+XIqqrzUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}