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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11703e58e3bbafdde731668c1d91a83fe211491e927aa3059a5a46f041b0235f' 
  AND token = 'zGAuCRB5IRYpxgysg6YHgexBRZE6H/OL9soLbUz5IxY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}