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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd0c2ad8463a8de9511d1a34b9d9aaf2eb945690fe9a04951b60679e965d47fe' 
  AND token = 'kd+wu5AdCV8pwwE1Qv0gCdwAUocCYVvY8xxtz9Y1JAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}