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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86f77d5d9eb9d71882ebd19216a8a0cafc55f87bc3e03b929dd42040cac56191' 
  AND token = 'b/yEQAoWZ8gEaqRyblNEguRiJvkzFDhPM8Bsbwu2w0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}