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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1785805590ef794d1c54c974b91a55a2cedc16c929df55093da8523bd139d464' 
  AND token = '6Nq9bQlgHYAkC0++z3p3KaQhmN+j5NhRpcMB1bJV1bc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}