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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1f64b77fa076616cc4b126a170ec777247c8d5074e9e368f3e06f345d1b6108' 
  AND token = 'PKpugXj05r9SuV58k94GQnbsTtcV+aLqoPiVy/0p8ec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}