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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb31bd22ebb065edfaba04670c427106280b94a535eefdfbbc1b29cb6d7f7ed2' 
  AND token = 'qIoNLCiDOIk2Xi/OIMvbqR5x+6FwQcojO4UlDu1JLOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}