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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3b053daa8a1fe29dd03c11b4ceb1cab2bd456b81e3e59ce4a2df090cf098551' 
  AND token = '0Y2lD01TZaltP46GtzF9Y/kThoHkGn0xIhY4xhyfZAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}