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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eedee9a365fdbf1f7e4449408d7b57614e710942b6d409cb2246bf419e6adc8c' 
  AND token = 'yyl3h1CcrigZYRHdLO1DjXxqTkLRZnMkquN2nzcB1mk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}