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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '701885ee385e84821c7b6a31797b16308f70143bf40df7fb9c3f4cd99d2427de' 
  AND token = '0KYuV76KdVWJJyLJ0l+E7tze7bVvs6i2umpYUFf2bz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}