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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '291f4a91cb759ef208dae264643b62ddcb991782b8c1c1840b159b4fb2414145' 
  AND token = 'zv07ESv82Gw2mmz4ob3kzXD+Q7tlLOjoTyXMXvRFly0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}