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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecc9809218a113606ac9ebc5ac9f4c14765bdc50776986bdbe50f3db46d84cd5' 
  AND token = 'GWfkmnP2Pql2sMRU8And9ZHN2/I/3XkPBsCfE91vIxE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}