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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6995c2617da96d301b0638b3ebe4891232d77d1a1995e8d5937fb5d030749b8d' 
  AND token = 'Fm/Uoj23h8Gcd8sevRmgq0My16N/GVwlEMpwbP1WHbs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}