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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd81b55d7f824775376537437d2c82e3a7be0243c78b7edfc0d07d2e94a6a77b' 
  AND token = '1RSsTUvUkfgbmeN6wLsIRo+8hF3S18pje4lCS9VjFhQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}