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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf10c7d58349833ee985c364fa063e7613ec6753e9f860a1ad8ad4a8cdd6a2aa' 
  AND token = 'YP2QbdUnJ0n7P1+NRtzzC57us/UxiK1a0Zm0hKwwnKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}