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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b19c11d293f53dfb990e50a0780841d1089829f4f963013b3de90fe487a38476' 
  AND token = 'pd9W8f3/DDPhA+JmshChFdmWV5Jx3myfbQddqFFkA+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}