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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7105875dda9c36d4ffc17079f6ce4cca8d513a1fd96b83ba3f9344f2033ac865' 
  AND token = 'dy3n6GaqK5GQAxRs/bADQLFIMqJCMOWM/G50Y/ZrwQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}