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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6851a4604b0c10224506f324dcdfb46f36c0dbf146af6b617fe607762c151d5' 
  AND token = 'judyAHfGqRhl7h3ZrJ01yRro72IRQnwwQOvObdaLasY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}