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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bea791e12d7fbd3ea739dac152e150ea70a248a6c9f0253ea7deedfe2f7c39b' 
  AND token = '3N4EvM26VUu3N7bAlKrT4u2RAY3+jOAHxtwbc0qQnwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}