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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '335c8758c19272d119dbc6bd616fb68a55ce1e510204f2e8f4d34ec8982a0e68' 
  AND token = 'NCAIErbVK2HN80PWR9mWms5MkAcCcVyd6OxXFMMJTgM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}