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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5f2345a91b954faf10ce02c7559a2e2b5bd352b54453603b086fb899d03b860' 
  AND token = 'EHaCbLbTRvRdhNwTlWWPd71+6Q3Ol/xenFDvpCKonlo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}