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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c5fb05496e19d5e27c9bceed14198749d585bc95cad6fe4dd43a7f0cbf669cc' 
  AND token = 'Oy8N/O/m/SthiL/ScCFmP80lOUUjIpEG3gu9U2mUUmg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}