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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d38443e7869a6ddd56608c94f4c8eb511de5c6eadfa91c3951bc537224a6da0' 
  AND token = 'wA3TGMxxzuckXdB+tz3dbnNPg3HCvC8nnlNKWv9TAwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}