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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f5b3a8b4b4925c861816a1c29b3d4b375e546a566eeb155352972afbac05993' 
  AND token = 'KHjx900WIBkw9iwXONcksH8kiedv2N06TVzYBys7qaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}