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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8af1e15ae2a2db89732bf7c84203a3f89901b675335b2f510323163789199c8' 
  AND token = 'rnow/xaJW8q2M+ePVWbr24b8nf68xT+EW9lXU6Ne7jI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}