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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50a89af680123f061d20d1541441a60d94883f4c3e1ecefdbb2b9c460dc852da' 
  AND token = 'w1Qx/LDxz6qucopaKv25nL5Cpshn6LBZU5D8p7uGMJc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}