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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2ba4912bbce38ad35808af109eaad6e4851a1c61dc2843bb709742b06405d29' 
  AND token = 'puBmqD7OUE03zAJaxo/mHexC5cUaKvoHl0m4VBgjvoQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}