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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d8a710780d716411eb0290c0d0d9ed9ddf44e77252bfd814abaf5d72e729988' 
  AND token = 'R0p33spSQjXJb6rmQBErPeDsWpmDIV6LMG4qMNKg1PE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}