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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b8e17bb0b405013ce2e4d5db0b390fbe8b7eb08e35441243224fdd83854b892' 
  AND token = 'BGcyuxBs/XHBvrIzXGk/WGjrhqAidBfMLcxLhxm/al4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}