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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb4bad6b4ba5c46c55a853c3c52270ff57113e8fcc673801d046aca1cde7b778' 
  AND token = 'jUMv4BLtgQzWzk7raCmO4hpyMROabSTD2VrjAFPxhVo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}