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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a760f383ca0928f5089062ce54cf1dec77d317f9d345ecbe5fe582bfed31490c' 
  AND token = '7EanUyd/N7M0cohjweoFW8IBryZnVIfk+K1ciqx24bg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}