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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f3f402f2013e50d0e1392b1f54b63508397279f318ff376ee76c17b0ebfd2f2' 
  AND token = 'f+0+eFMUXxkTlIHByXTvzBhtkSIZh0Fnm+pI4qo4pVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}